Abuse and misuse of benzodiazepines often (but not always) involve the use of doses greater than the maximum recommended dosage and commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes, including respiratory depression, overdose, or death. a history of depression or suicidal thoughts or behavior; The bioavailability and pharmacokinetics of alprazolam following administration of XANAX XR are similar to that for XANAX, with the exception of a slower rate of absorption. WebXANAX XR (ALPRAZOLAM) 2MG PFIZER $150.00 $1,900.00 XANAX XR (ALPRAZOLAM) 2MG MAIN SUBSTANCE : Alpazolam CATEGORY : Benzo MANUFACTURER : Pfizer DOSAGE : 2-4 tabs/day PACKAGE : 2mg/tab 50 tabs Choose an Option Choose an option1 BOTTLE - 50 TABS2 BOTTLES - 100 TABS4 BOTTLES - 200 TABS6 BOTTLES - 300 TABS8 The risks of dependence and withdrawal increase with longer treatment duration and higher daily dose. Its also available as a generic drug. Although interactions between benzodiazepines and commonly employed clinical laboratory tests have occasionally been reported, there is no consistent pattern for a specific drug or specific test. Reduce the dosage by no more than 0.5 mg every three days. Pharmacists can take an active role in preventing counterfeit drugs by ensuring that they source products only from a reputable wholesaler or distributor. narrow-angle glaucoma; However, the carbamazepine dose used in this study was fairly low compared to the recommended doses (10001200 mg per day); the effect at usual carbamazepine doses is unknown. Alprazolam also comes as a solution. WebThe use of benzodiazepines, including XANAX, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. Do not take more XANAX XR than prescribed or take XANAX XR for longer than prescribed. Inactive ingredients: Cellulose, corn starch, docusate sodium, lactose, magnesium stearate, silicon dioxide and sodium benzoate. Users who take Xanax report feeling the following effects: A calming sensation Feelings Vaccination requires two doses given three weeks apart. Xanax is a brand-name pill that contains alprazolam. Pfizer. All forms are taken by mouth. The mean dose of XANAX XR at the last treatment visit was 4.2 mg per day in the first study and 4.6 mg per day in the second. WebPfizer Xanax Packaging & Bottle. In addition, the 0.5 mg tablet contains FD&C Yellow No. Each segment is meant to be a single 0.5 mg dose of Xanax. Do not drive, operate heavy machinery, or do other dangerous activities until you know how XANAX XR affects you. Protect from light. Dosage adjustment is necessary when XANAX XR and ritonavir are initiated concomitantly or when ritonavir is added to a stable dosage of XANAX XR [see Dosage and Administration (2.5), Drug Interactions (7.1)]. XANAX XR can make you sleepy or dizzy and can slow your thinking and motor skills. Alprazolam concentrations may be reduced by up to 50% in smokers compared to non-smokers. The service is difficult to criticize. Other brand names, as well as Do not use XANAX XR for a condition for which it was not prescribed. Dosage reduction of XANAX XR is recommended in patients with hepatic impairment [see Dosage and Administration (2.4), Clinical Pharmacology (12.3)]. I purchase Xanax 1mg from usamedzone online, the product I have received is absolutely real and Original. Xanax is a powerful Benzodiazepine that is often prescribed to treat generalized anxiety disorder (GAD), panic disorders, and insomnia. I will recommend it. Alprazolam is a white crystalline powder, which is soluble in methanol or ethanol but which has no appreciable solubility in water at physiological pH. Ava is a digital health aid for womens health including cycle tracking, fertility, and pregnancy. Oral Contraceptives: Coadministration of oral contraceptives increased the maximum plasma concentration of alprazolam by 18%, decreased clearance by 22%, and increased T1/2 by 29%. Alprazolam is a 1,4 benzodiazepine. In order to better understand the underground market for this drug, StreetRx collects data on the street price of Xanax and has found that its average black-market price is approximately $7. WebA white Xanax bar contains 2 mg in one whole pill, but can easily be split into four different segments. The products discussed herein may have different labeling in different countries. Please visit Viatris.com for the most current product information. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. Use the search tool below to find Pfizer distributors of Greenstone products in the United States and Puerto Rico. WebXanax is the single most prescribed psychiatric drug in the United States; belongs to the benzodiazepines group of drugs. Drug abuse and dependence: Even when used as recommended, alprazolam may cause emotional or physical dependence (addiction). If an overdose occurs, consult a Certified Poison Control Center at 1-800-222-1222 for the latest recommendations. In patients with hepatic impairment, the recommended starting dosage of XANAX XR is 0.5 mg once daily. Unleashing the next wave of scientific innovations, Research and Business Development Partnerships. Advise patients not to drive or operate heavy machinery until the effects of concomitant use with the opioid have been determined [see Drug Interactions (7.1)]. XANAX XR U.S. Abuse and misuse of benzodiazepines often (but not always) involve the use of doses greater than the maximum recommended dosage and commonly involve concomitant use of other medications, alcohol, and/or illicit substances, which is associated with an increased frequency of serious adverse outcomes, including respiratory depression, overdose, or death, To reduce the risk of withdrawal reactions, use a gradual taper to discontinue XANAX XR or reduce the dosage (a patient-specific plan should be used to taper the dose), The continued use of benzodiazepines, including XANAX XR, may lead to clinically significant physical dependence. Most patients showed a response in the dosage range of 3 mg to 6 mg per day. As a result, there may be difficulty in differentiating withdrawal symptoms from potential re-emergence or continuation of symptoms for which the benzodiazepine was being used. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). 6 and the 1 mg tablet contains FD&C Blue No. Buy xanax online no prescription, a brand name of alprazolam, Xanax is generally prescribed for anxiety linked with depression, generalized anxiety disorder, and panic disorder. ( 1) DOSAGE AND ADMINISTRATION Recommended starting oral dosage is 0.5 mg to 1 mg once daily (preferably in the morning). Reports of serious side effects, such as allergic reactions, are very rare; no long-term complications have been reported. These doses are 29 times and 4.8 times the maximum recommended human dose of 10 mg/day based on mg/m2 body surface area, respectively. The benzodiazepines, including alprazolam, produce additive CNS depressant effects when coadministered with other CNS depressants. WebPill with imprint X 2 is Blue, Round and has been identified as Xanax XR 2 mg. As of 30 March 2021, Pfizer and BioNTech aimed to manufacture about 2.5billion doses in 2021. Physician Prescribing Information. Further increase in the dose (up to 0.5-0.75 mg / day) is carried out with caution for good tolerability of the drug. Physician Prescribing Information. In patients on digoxin therapy, measure serum digoxin concentrations before initiating XANAX XR. buy the best quality steroids. Drowsiness Elderly patients are especially susceptible to dose related adverse effects when taking XANAX XR. USD 105.00 USD 90.00 - + Add to cart Add to Wishlist The following clinically significant adverse reactions are described elsewhere in the labeling: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. WebWomen's Health. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. XANAX XR is contraindicated in patients receiving strong inhibitors of CYP3A such as azole antifungal agents [see Contraindications (4)]. Drugs demonstrated to be CYP3A inhibitors on the basis of clinical studies involving alprazolam: nefazodone, fluvoxamine, and cimetidine [see Drug Interaction (7.1), Clinical Pharmacology (12.3)]. Set id: aa58fff3-c297-49be-838b-599c32ad9835, WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS. Your email address will not be published. If a patient develops withdrawal reactions, consider pausing the taper or increasing the dosage to the previous tapered dosage level. The support staff is very helpful and polite. Abuse is the intentional, non-therapeutic use of a drug, even once, for its desirable psychological or physiological effects. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to XANAX XR during pregnancy. Advise patients to inform their healthcare provider of all medicines they take, including prescription and nonprescription medications, vitamins and herbal supplements [see Drug Interactions (7)]. Take XANAX XR exactly as your healthcare provider prescribed. September 30, 2022, A straightforward ordering system with quick delivery at good prices. In some cases, benzodiazepine users have developed a protracted withdrawal syndrome with withdrawal symptoms lasting weeks to more than 12 months [see Drug Abuse and Dependence (9.3)]. Monitoring of the primary outcomes from the trials will continue until August 2021, while monitoring of the secondary outcomes will continue until January 2023. WebXanax Pfizer 2mg. -Trouble breathing Imipramine and Desipramine: The steady state plasma concentrations of imipramine and desipramine have been reported to be increased an average of 31% and 20%, respectively, by the concomitant administration of XANAX in doses up to 4 mg per day. Xanax is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). Order now. Genocide North America 2025: United States of America (Click the graphic above to view the original archived page) COVID-19 Vaccination in the United States of America (to June 2021) 174,234,573 people Also, dont stop taking this medication suddenly or decrease the dosage without talking to your doctor. Though Xanax does have legitimate medical uses, some people abuse it or take it recreationally. See full prescribing information for complete boxed warning. Some patients may prove resistant to all discontinuation regimens. See full prescribing information for XANAX XR. WebXanax is the single most prescribed psychiatric drug in the United States; belongs to the benzodiazepines group of drugs. (of a stimulus or mental process) below the threshold of sensation or consciousness; perceived by or affecting someones mind without their being aware of it. For the most recent prescribing information, please visit www.pfizer.com. 4 yr. ago Damn, whats up with all the downvotes? Prescribe the least number of tablets feasible to avoid intentional overdosage. WebHigher dosage amounts (e.g. Before you take XANAX XR, tell your healthcare provider about all of your medical conditions, including if you: Tell your healthcare provider about all the medicines you take. Death is more often associated with polysubstance use (especially benzodiazepines with other CNS depressants such as opioids and alcohol). Analyses of the relationship between treatment outcome and gender did not suggest any differential responsiveness on the basis of gender. Alprazolam is 80% bound to human serum protein, and albumin accounts for the majority of the binding. (, Patients with Depression: Exercise caution in patients with signs or symptoms of depression. Product Images Compare . Taking benzodiazepines with opioid medicines, alcohol, or other central nervous system (CNS) depressants (including street drugs) can cause severe drowsiness, breathing problems (respiratory depression), coma and death. WebThis product information is intended only for residents of the United States. Alprazolam is in a class of medications called benzodiazepines. To report SUSPECTED ADVERSE REACTIONS, contact Pfizer Inc. at 1-800-438-1985 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. Alprazolam was negative in the in vitro Ames bacterial reverse mutation assay and DNA Damage/Alkaline Elution Assay and in vivo rat micronucleus genetic toxicology assays. Had a duplicate order which was rectified almost upon receipt of email to customer care .then I had it delivered super fast . Call your healthcare provider or go to the nearest hospital emergency room right away if you get any of the following symptoms. See 17 for PATIENT COUNSELING INFORMATION and Medication Guide. Occasional patients required as much as 10 mg per day. Serious side effects including coma and death have happened in people who have abused or misused benzodiazepines, including XANAX XR. There are reports of sedation and withdrawal symptoms in breastfed neonates and infants exposed to alprazolam. Easy to order and reorder. This product's labeling may have been updated. Alprazolam exposure was not meaningfully affected in the presence of ritonavir. This drug attaches to certain benzodiazepine receptors in your brain and nervous system. ( 1) DOSAGE AND ADMINISTRATION Recommended starting oral dosage is 0.5 mg to 1 mg once daily (preferably in the morning). Xanax XR is used in the treatment of panic disorder and belongs to the drug class benzodiazepines . XANAX XR may harm your unborn baby. The most common side effects include mild to moderate pain at the injection site, fatigue, and headaches. (5.2) Abrupt discontinuation or rapid dosage reduction of XANAX after XANAX XR is a registered trademark of Pharmacia & Upjohn Company LLC. Drug products that have been studied in vivo, along with their effect on increasing alprazolam AUC, are as follows: ketoconazole, 3.98 fold; itraconazole, 2.66 fold; nefazodone, 1.98 fold; fluvoxamine, 1.96 fold; and erythromycin, 1.61 fold [see Contraindications (4), Warnings and Precautions (5.5), Drug Interactions (7.2)]. After a period of extended freedom from panic attacks, a carefully supervised tapered discontinuation may be attempted, but there is evidence that this may often be difficult to accomplish without recurrence of symptoms and/or the manifestation of withdrawal phenomena [see Dosage and Administration (2.2), Warnings and Precautions (5.2)]. Before prescribing XANAX and throughout treatment, assess each patients risk for abuse, misuse, and addiction. Fluoxetine: Coadministration of fluoxetine with alprazolam increased the maximum plasma concentration of alprazolam by 46%, decreased clearance by 21%, increased T1/2 by 17%, and decreased measured psychomotor performance. Short term administration of ritonavir increased alprazolam exposure due to CYP3A4 inhibition. WebPfizer Xanax 2mg Bars, 60 Pills In A Pack, Prescription Get Latest Price - Each XANAX tablet, for oral administration, contains 0.25 mg, 0.5 mg, 1 mg, or 2 mg of alprazolam. (, Use with CYP3A Inducers: Increase the risk of reduced efficacy of alprazolam. Maximal concentrations and T1/2 of alprazolam are approximately 15% and 25% higher in Asians compared to Caucasians. It is dangerous to purchase Xanax on the Internet or outside the United States. Dispense in tight (USP), light-resistant, child-resistant containers. The concomitant use of benzodiazepines and opioids increases the risk of respiratory depression because of actions at different receptor sites in the CNS that control respiration. Use caution and consider dose reduction of XANAX XR, as appropriate, during co-administration with these drugs. Healthcare providers are encouraged to register patients by calling the National Pregnancy Registry for Other Psychiatric Medications at 1-866-961-2388 or visiting online at https://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/othermedications/. XANAX XR is a prescription medicine used to treat panic disorder, with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia). Each XANAX XR extended-release tablet, for oral administration, contains 0.5 mg, 1 mg, 2 mg, or 3 mg of alprazolam. Compounds that are inhibitors or inducers of CYP3A would be expected to increase or decrease plasma alprazolam concentrations, respectively. Genocide North America 2025: United States of America (Click the graphic above to view the original archived page) COVID-19 Vaccination in the United States of America (to June 2021) 174,234,573 people Xanax is used in the treatment of anxiety; panic disorder; depression and belongs to the drug class benzodiazepines. Follow patients for signs and symptoms of respiratory depression and sedation, The use of benzodiazepines, including XANAX XR, exposes users to risks of abuse, misuse, and addiction, which can lead to overdose or death. Do not share your XANAX XR with other people. Highly recommend Pharmacy. Store at controlled room temperature, 20 to 25C (68 to 77F) [see USP]. Reserve concomitant prescribing of these drugs for use in patients for whom alternative treatment options are inadequate. Neonates born to mothers using benzodiazepines during the later stages of pregnancy have been reported to experience symptoms of sedation and neonatal withdrawal [see Warnings and Precautions (5.4), Clinical Considerations)]. Other studied drugs include: Cimetidine: Coadministration of cimetidine increased the maximum plasma concentration of alprazolam by 82%, decreased clearance by 42%, and increased T1/2 by 16%. Adverse Reactions Occurring at an Incidence of 1% or More Among Patients Treated with XANAX XR. Begin with minimal doses of Xanax xr (0.25-0.5 mg / day), followed by a rise first in the evening and then in the daytime. Thanks usamedzone.com WebPfizer Xanax 2mg Bars, 60 Pills In A Pack, Prescription Get Latest Price - Each XANAX tablet, for oral administration, contains 0.25 mg, 0.5 mg, 1 mg, or 2 mg of alprazolam.